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Daphne P. Ly, M.D.

Daphne P. Ly, M.D.

Clinical Fellow (PGY-6)
Breast Surgical Oncology

Contact Information

Phone: 415-353-7070
Daphne.Ly@ucsf.edu
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  • San Jose State University, San Jose, CA, B.A. Mathematics with concentration in Computer Science, 1986
  • Albert Einstein College of Medicine, Bronx, NY, M.D., 1998
  • UMDNJ Robert Wood Johnson Medical School, General Surgery, 1998 – 2005
  • Research Fellowship in Wound Healing, Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, 2005-2008
  • Surgical Critical Care, Stanford University School of Medicine, 2008-2009
  • American Board of Surgery, General Surgery
  • American Board of Surgery, Surgical Critical Care
  • UCSF Department of Surgery
  • UCSF Carol Franc Buck Breast Care Center
  • Breast Surgical Oncology
  • Application of cancer genetics in individualizing cancer care
  • Data analysis in clinical trials and breast cancer care
  • DCIS histopathology
  • Integration of computer science in automation of data collection

Dr. Daphne Ly is a breast surgical oncology clinical fellow in the Department of Surgery. She received her BA from San Jose State University in 1987 in Mathematics with concentration in Computer Science. She worked as a software engineer for seven years prior to starting medical school. She received her MD degree from Albert Einstein College of Medicine with Honor Diploma for Research in Basic Sciences.

Dr. Ly went on to receive her General Surgery residency training at UMDNJ Robert Wood Johnson Medical School from 1998 to 2005. During residency, Dr. Ly's research focused on the role of integrins in wound healing. She continued her research in Wound Healing at the Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine from 2005 to 2008. Dr. Ly stayed on to complete a fellowship in Surgical Critical Care. Dr. Ly is boarded in both General Surgery and Surgical Critical Care. She is also a member of the ACS National Ultrasound Faculty. She is an avid ultrasound user and passionate in teaching the clinical applications of ultrasound to General Surgery residents at Stanford University School of Medicine and UCSF.

Dr. Ly's research interests include application of cancer genetics in individualizing cancer care, DCIS histopathology, and integration of computer science in automation of data collection and data analysis in clinical trials and breast cancer care

Most recent publications from a total of 12
  1. Steffel L, Kim TE, Howard SK, Ly DP, Kou A, King R, Mariano ER. Comparative Effectiveness of Two Ultrasound-Guided Regional Block Techniques for Surgical Anesthesia in Open Unilateral Inguinal Hernia Repair. J Ultrasound Med. 2016 Jan; 35(1):177-82. View in PubMed
  2. Lahti JL, Lui BH, Beck SE, Lee SS, Ly DP, Longaker MT, Yang GP, Cochran JR. Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation. FEBS Lett. 2011 Apr 20; 585(8):1135-9. View in PubMed
  3. Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, Butler PD, Yang GP, Joshua B, Kaplan MJ, Longaker MT, Weissman IL. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010 Jul 01; 466(7302):133-7. View in PubMed
  4. Parent RJ, Plerhoples TA, Long EE, Zimmer DM, Teshome M, Mohr CJ, Ly DP, Hernandez-Boussard T, Curet MJ, Dutta S. Early, intermediate, and late effects of a surgical skills "boot camp" on an objective structured assessment of technical skills: a randomized controlled study. J Am Coll Surg. 2010 Jun; 210(6):984-9. View in PubMed
  5. Butler PD, Wang Z, Ly DP, Longaker MT, Koong AC, Yang GP. Unfolded protein response regulation in keloid cells. J Surg Res. 2011 May 01; 167(1):151-7. View in PubMed
  6. Lopes LB, Furnish EJ, Komalavilas P, Flynn CR, Ashby P, Hansen A, Ly DP, Yang GP, Longaker MT, Panitch A, Brophy CM. Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts. J Invest Dermatol. 2009 Mar; 129(3):590-8. View in PubMed
  7. Butler PD, Ly DP, Longaker MT, Yang GP. Use of organotypic coculture to study keloid biology. Am J Surg. 2008 Feb; 195(2):144-8. View in PubMed
  8. Chang EI, Ly DP, Wey PD. Comparison of aesthetic breast reconstruction after skin-sparing or conventional mastectomy in patients receiving preoperative radiation therapy. Ann Plast Surg. 2007 Jul; 59(1):78-81. View in PubMed
  9. Ly DP, Liao JG, Burd RS. Effect of surgeon and hospital characteristics on outcome after pyloromyotomy. Arch Surg. 2005 Dec; 140(12):1191-7. View in PubMed
  10. Ly DP, Corbett SA. The integrin alpha5beta1 regulates alphavbeta3-mediated extracellular signal-regulated kinase activation. J Surg Res. 2005 Feb; 123(2):200-5. View in PubMed
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Publications provided by UCSF Profiles, powered by CTSI at UCSF. View profile of Daphne P. Ly, M.D.
Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.
  1. Ly D.P., Lahti J.L., Beck S.E., Lee S.S., Longaker M.T., Yang G.P., Cochran J.R. Enhanced Biological Function of Engineered EGF Is Correlated with Faster On-rates of Receptor Binding. (Abstract presented at the the 4th Annual Academic Surgical Congress. February 2009).
  2. Butler P.D., Ly D.P., Longaker M.T., Koong A.C., Huang E.J., Yang G.P. Targeted Deletion of HIPK2 Leads To Improved Cell Survival in Response to Endoplasmic Reticular Stress. (Abstract presented at the 4th Annual Academic Surgical Congress. February 2009).
  3. Parent R., Long E., Zimmer D., Teshome M., Ly D.P., Mohr C., Hernandez-Boussard M., Curet M. Dutta S. Early and Intermediate Effects of A Surgical Skill "Boot Camp" on An Objective Assessment of Technical Skills: A Randomized Controlled Study. (Abstract presented at the 4th Annual Academic Surgical Congress. February 2009).
  4. Ly D.P., Beck S.E., Lee S.S., Longaker M.T., Cochran J.R., and Yang G.P. Enhanced In Vitro Activity of Engineered EGF is Correlated with Improved Wound Healing in A Mouse Model. (Abstract presented at the 3rd Annual Academic Surgical Congress. February 2008).
  5. Butler P. D., Ly D.P., Wang Z., Longaker M.T., and Yang G.P. Use of Organotypic Skin Culture to Study Keloid Biology. (Abstract presented at the American College of Surgeons 93rd Annual Clinical Congress. October 2007).
  6. Ly D.P., Beck S.E., Lee S.S., Longaker M.T., Cochran J.R., and Yang G.P. Engineered Epidermal Growth Factor for Wound Healing Applications. (Abstract presented at the Plastic Surgery Research Council 52nd Annual Meeting. June 2007).
  7. Beck S.E., Ly D.P., Lee S, Longaker M, Yang G, Cochran J. Engineering High Affinity Epidermal Growth Factor Mutants for Wound Healing Applications. (Poster at Experimental Biology Annual Meeting. April 2007). Ly D.P., Lee S.S., Longaker M.T., Cochran J.R., and Yang G.P. Effects of Engineered EGF Mutants on Fibroblast Biological Functions. (Abstract presented at the Society of University Surgeons section of the 2nd Annual Academic Surgical Congress. February 2007).
  8. Ly D.P., Raj B.M., and Corbett S.A. alpha5beta1 Regulates alphavbeta3-mediated Cell Survival on Fibrinogen. (Abstract presented at the Society of University Surgeons 64th Annual Meeting. February 2003).
  9. Ly D.P., Zazzali K.M., and Corbett S.A. Alpha5beta1 Regulates alphavbeta3-mediated Cell Migration via the ERK/MAPK Signaling Pathway (Abstract presented at the Association for Academic Surgery 36th Annual Meeting. November 2002).
  10. Ly D.P., Zazzali K.M., and Corbett S.A. Alpha5beta1 Regulation of Cell Migration is Mediated by the Cytoplasmic Tail of the alpha5 Subunit (Abstract presented at the Association for Academic Surgery 35th Annual Meeting. November 2001).
  11. Ly D.P., Rumalla V.K., and Wey P.D. Aesthetic Breast Reconstruction after Radiation Therapy (Abstract presented at the ASPS/PSEF/ASMS 70th Annual Scientific Meeting. November 2001).
  12. Ly D.P., Zazzali K.M., and Corbett S.A. A Novel Role for the Integrin alpha5beta1 in the Regulation of Cell Migration (Abstract presented and published in Proceedings for the 56th Annual Sessions of the Owen H. Wangensteen Surgical Forum 2001 Clinical Congress. (October 2001). Vol 52, p. 551).
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