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Jeremy M. Sharib, M.D.

Jeremy M. Sharib, M.D.

Chief Resident (PGY-5)
General Surgery 

Contact Information

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  • University of Rochester, 2007 BS Biomedical Engineering, 2007, Certificate of Management Studies
  • University of California Irvine, 2013 MD
  • 2013-14 Surgical Intern, UCSF
  • 2014-present Surgical Resident, UCSF
  • Surgical Oncology
  • Pancreatic Cysts
  • Pancreatic Cancer
  • Pancreatic Cancer
  • IPMN
  • Pancreatic Cysts
I am a General Surgery Resident, currently completing two years of research in the department of Pharmaceutical Chemistry under the mentorship of Kimberly Kirkwood and Charles Craik. My work aims to understand the role of protease dysregulation in mucinous pancreatic cysts and pancreatic cancer. I am also interested in discovering genetic and protease activity based biomarkers for potentially malignant cysts. My clinical interest is similarly, to improve diagnosis and management of IPMN, a type of Pancreatic Cyst. Following General Surgery training, I plan to complete a fellowship in Surgical Oncology.
Resident shown in bold. Research Mentor(s) shown in color.
  1. Wang MT, Fer N, Galeas J, Collisson EA, Kim SE, Sharib J, McCormick F. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019 Jul 11; 10(1):3055. View in PubMed
  2. Ivry SL, Knudsen GM, Caiazza F, Sharib JM, Jaradeh K, Ravalin M, O'Donoghue AJ, Kirkwood KS, Craik CS. The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts. Biol Chem. 2019 Jul 01. View in PubMed
  3. Sharib JM, Fonseca AL, Swords DS, Jaradeh K, Bracci PM, Firpo MA, Hatcher S, Scaife CL, Wang H, Kim GE, Mulvihill SJ, Maitra A, Koay EJ, Kirkwood KS. Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making? Surgery. 2018 12; 164(6):1178-1184. View in PubMed
  4. Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS. Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts. Clin Cancer Res. 2017 Aug 15; 23(16):4865-4874. View in PubMed
  5. Sharib J, Kirkwood K. Early and accurate diagnosis of pancreatic cancer? Oncotarget. 2016 12 27; 7(52):85676-85677. View in PubMed
  6. Aghighi M, Boe J, Rosenberg J, Von Eyben R, Gawande RS, Petit P, Sethi TK, Sharib J, Marina NM, DuBois SG, Daldrup-Link HE. Three-dimensional Radiologic Assessment of Chemotherapy Response in Ewing Sarcoma Can Be Used to Predict Clinical Outcome. Radiology. 2016 09; 280(3):905-15. View in PubMed
  7. Sharib J, Horvai A, Gray Hazard FK, Daldrup-Link H, Goldsby R, Marina N, DuBois SG. Comparison of Latino and non-Latino patients with Ewing sarcoma. Pediatr Blood Cancer. 2014 Feb; 61(2):233-7. View in PubMed
  8. Sharib J, Truntzer J, Young J, Jordan G, Gelman J. Panurethral stricture after photovaporization of the prostate for benign prostatic hyperplasia. J Endourol. 2012 May; 26(5):520-3. View in PubMed
  9. Sharib JM, Cyrus J, Horvai A, Gray Hazard FK, Neuhaus J, Matthay KK, Goldsby R, Marina N, DuBois SG. Predictors of acute chemotherapy-associated toxicity in patients with Ewing sarcoma. Pediatr Blood Cancer. 2012 Oct; 59(4):611-6. View in PubMed
  10. Harzstark AL, Rosenberg JE, Weinberg VK, Sharib J, Ryan CJ, Smith DC, Pagliaro LC, Beer TM, Liu G, Small EJ. Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: a phase 2 study of the Department Of Defense Prostate Cancer Clinical Trials Consortium. Cancer. 2011 Jun 01; 117(11):2419-25. View in PubMed
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