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Ryutaro Hirose, M.D.

Ryutaro Hirose, M.D.

Professor of Clinical Surgery 
Division of Transplant Surgery
Associate Program Director,
UCSF General Surgery Residency Program

Contact Information

(415) 353-1888 Clinical, Liver
(415) 353-1551 Clinical, Kidney and Pancreas
(415) 353-8783 Academic
Ryutaro.Hirose@ucsfmedctr.org   
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  • Columbia College, Columbia University, B.A., Mathematics, 1981-85
  • Columbia University College of Physicians And Surgeons, M.D., 1985-89
  • University of California, San Francisco, Intern and Resident, Surgery, 1989-92
  • University of California, San Francisco, Resident, Surgery, 1995-96
  • University of California, San Francisco, Chief Resident, Surgery, 1996-97 
  • University of California, San Francisco, Fellow, Transplant Surgery, 1997-99
  • University of California, San Francisco, Postdoctoral Fellow, Molecular Medicine, 1992-95
  • American Board of Surgery, 1998
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Complex Cancer Resections
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney Transplantation
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Pancreas Transplants
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Radio Frequency Ablation (RFA)
  • Surgical Shunts
  • Ischemia Reperfusion Injury in Fatty Livers
  • Ischemia-reperfusion Injury in Kidneys and Hyperglycemia
  • Living Donor Liver Transplantation
  • Non-melanoma Skin Cancer in Organ Transplant Patients
  • Outcomes in Renal Transplant Recipients
  • Pathogenesis of Focal Segmental Glomerulosclerosis

Ryutaro Hirose is a Professor of Clinical Surgery at UCSF and performs liver, kidney and pancreas transplants. After graduating from Columbia College of Physicians and Surgeons, he completed his clinical and research training at UCSF as a resident in general surgery as well as a fellow in molecular medicine and transplantation surgery. His research interests include renal and hepatic ischemia - reperfusion injury, immune monitoring and skin cancer in transplant recipients. He has received funding from the NIH, NKF, UCSF, ASTS, and private industry. He is also actively involved with teaching students and residents. Dr. Hirose is currently the Associate Program Director for the General Surgery Residency at UCSF.

Dr. Hirose's research focus is ischemia-reperfusion injury and potential interventions to ameliorate renal and hepatic I-R injury. His group uses animal models, performs clinical and translational research as well as research on deceased donors. He collaborates with Dr. Claus Niemann, MD from the Dept. Anesthesia and they are co-Directors of the Ischemic Organ Injury Lab.

Most recent publications from a total of 78
  1. Roll GR, Webber AB, Gae DH, Laszik Z, Tavakol M, Mayen L, Cunniffe K, Syed S, Hirose R, Freise C, Feng S, Roberts JP, Ascher NL, Stock PG, Rajalingam R. A virtual crossmatch based strategy facilitates sharing of deceased donor kidneys for highly sensitized recipients. Transplantation. 2019 Aug 19. View in PubMed
  2. Parekh JR, Hirose R, Foley DP, Grieco A, Cohen ME, Hall BL, Ko CY, Greenstein S. Beyond death and graft survival-Variation in outcomes after kidney transplantation. Results from the NSQIP Transplant beta phase. Am J Transplant. 2019 Apr 12. View in PubMed
  3. Parekh JR, Greenstein S, Sudan DL, Grieco A, Cohen ME, Hall BL, Ko CY, Hirose R. Beyond death and graft survival-Variation in outcomes after liver transplant. Results from the NSQIP transplant beta phase. Am J Transplant. 2019 Jul; 19(7):2108-2115. View in PubMed
  4. Hirose R. State-Based Liver Allocation: Is It a Viable Alternative? Liver Transpl. 2019 Apr; 25(4):535-537. View in PubMed
  5. Mehta N, Dodge JL, Hirose R, Roberts JP, Yao FY. Predictors of low risk for dropout from the liver transplant waiting list for hepatocellular carcinoma in long wait time regions: Implications for organ allocation. Am J Transplant. 2019 Mar 12. View in PubMed
  6. Gao Y, Twigg AR, Hirose R, Roll GR, Nowacki AS, Maytin EV, Vidimos AT, Rajalingam R, Arron ST. Association of HLA Antigen Mismatch With Risk of Developing Skin Cancer After Solid-Organ Transplant. JAMA Dermatol. 2019 Jan 23. View in PubMed
  7. Mehta N, Dodge JL, Roberts JP, Hirose R, Yao FY. Alpha-Fetoprotein Decrease from > 1,000 to < 500 ng/mL in Patients with Hepatocellular Carcinoma Leads to Improved Posttransplant Outcomes. Hepatology. 2019 Mar; 69(3):1193-1205. View in PubMed
  8. Bertsimas D, Kung J, Trichakis N, Wang Y, Hirose R, Vagefi PA. Development and validation of an optimized prediction of mortality for candidates awaiting liver transplantation. Am J Transplant. 2019 Apr; 19(4):1109-1118. View in PubMed
  9. Cooper M, Formica R, Friedewald J, Hirose R, O'Connor K, Mohan S, Schold J, Axelrod D, Pastan S. Report of National Kidney Foundation Consensus Conference to Decrease Kidney Discards. Clin Transplant. 2019 Jan; 33(1):e13419. View in PubMed
  10. Mehta N, Dodge JL, Hirose R, Roberts JP, Yao FY. Increasing Liver Transplantation Wait-List Dropout for Hepatocellular Carcinoma With Widening Geographical Disparities: Implications for Organ Allocation. Liver Transpl. 2018 10; 24(10):1346-1356. View in PubMed
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